Glucose, insulin and myocardial ischaemia.

  title={Glucose, insulin and myocardial ischaemia.},
  author={Philippe Devos and R. -L. Chiolero and Greet Van den Berghe and Jean-Charles Preiser},
  journal={Current opinion in clinical nutrition and metabolic care},
  volume={9 2},
PURPOSE OF REVIEW The importance of glucose metabolism and insulin therapy during myocardial ischaemia is increasingly being investigated. Insulin is used to achieve a tight glucose control or as part of glucose-insulin-potassium therapy. We have reviewed (1) the physiological and physiopathological consequences of hyperglycaemia focusing on potential machanisms of myocardial ischaemia, (2) the effects of insulin on vascular tone, on the release of free fatty acids, on inflammatory pathways, on… CONTINUE READING