Glucose, insulin, and insulin-like growth factor I regulate the glycogen content of astroglia-rich primary cultures.

@article{Dringen1992GlucoseIA,
  title={Glucose, insulin, and insulin-like growth factor I regulate the glycogen content of astroglia-rich primary cultures.},
  author={Ralf Dringen and Bernd Hamprecht},
  journal={Journal of neurochemistry},
  year={1992},
  volume={58 2},
  pages={
          511-7
        }
}
The glycogen content of astroglia-rich primary cultures derived from the brains of newborn rats depends on the concentration of glucose in the culture medium. After administration of culture medium lacking glucose, the glycogen content decreases with a half-time of 7 min. Readdition of glucose results in replenishment of the glycogen stores within 2-3 h, but fully only if glucose is present in a concentration of at least 4 mM. Insulin, or the more potent insulin-like growth factor I, increases… CONTINUE READING
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