Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study.

@article{Pavelka2002GlucosamineSU,
  title={Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study.},
  author={Karel Pavelka and Jindři{\vs}ka Gatterov{\'a} and Marta Olej{\'a}rov{\'a} and S. Machacek and Giampaolo Giacovelli and Lucio Claudio Rovati},
  journal={Archives of internal medicine},
  year={2002},
  volume={162 18},
  pages={
          2113-23
        }
}
  • Karel Pavelka, Jindřiška Gatterová, +3 authors Lucio Claudio Rovati
  • Published in Archives of internal medicine 2002
  • Medicine
  • BACKGROUND Conventional symptomatic treatments for osteoarthritis do not favorably affect disease progression. The aim of this randomized, placebo-controlled trial was to determine whether long-term (3-year) treatment with glucosamine sulfate can modify the progression of joint structure and symptom changes in knee osteoarthritis, as previously suggested. METHODS Two hundred two patients with knee osteoarthritis (using American College of Rheumatology criteria) were randomized to receive oral… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 361 CITATIONS, ESTIMATED 54% COVERAGE

    Hip Osteoarthritis in General Practice: Course and Therapies

    VIEW 5 EXCERPTS
    CITES METHODS & BACKGROUND
    HIGHLY INFLUENCED

    Evidenzbasierte Bewertung der symptomatischen Therapie von Glucosamin

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    1998
    2019

    CITATION STATISTICS

    • 29 Highly Influenced Citations

    • Averaged 16 Citations per year from 2017 through 2019

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 59 REFERENCES

    The clinical profile of glucosamine sulfate as a selective symptom modifying drug in osteoarthritis: current data and perspectives [abstract

    • LC Rovati
    • Osteoarthritis Cartilage
    • 1997
    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    An assessment of clinically useful mea(REPRINTED) ARCH INTERN MED/ VOL 162

    • A Laupacis, DL Sackett, RS. Roberts
    • OCT 14,
    • 2002
    VIEW 1 EXCERPT

    Glucosamine sulfate inhibits nitric oxide and stromelysin production in cartilage cultures and reverses IL-1 inhibition of osteoarthritic articular cartilage synthesis [abstract

    • I Yaron, I Shirazi, R Judovich, M. Yaron
    • Ann Rheum Dis
    • 2001

    Glucosamine sulfate inhibits nitric oxide and stromelysin production in cartilage cultures and reverses IL-1 inhibition of osteoarthritic articular cartilage synthesis [abstract

    • I Yaron, I Shirazi, R Judovich, M. Yaron
    • Ann Rheum Dis
    • 2001