Glucosamine reverses drug resistance in MRP2 overexpressing ovarian cancer cells.

@article{Sani2019GlucosamineRD,
  title={Glucosamine reverses drug resistance in MRP2 overexpressing ovarian cancer cells.},
  author={Fatemeh Valinezhad Sani and Abbasali Palizban and F. Mosaffa and K. Jamialahmadi},
  journal={European journal of pharmacology},
  year={2019},
  pages={
          172883
        }
}
  • Fatemeh Valinezhad Sani, Abbasali Palizban, +1 author K. Jamialahmadi
  • Published 2019
  • Chemistry, Medicine
  • European journal of pharmacology
  • Glucosamine (GlcN), a natural amino sugar in human body, was reported to exhibit anticancer activity against some tumors. In the present study, we evaluated the cytotoxicity and multi-drug resistance (MDR) reversal activity of GlcN on resistant MRP2-overexpressing ovarian cancer A2780RCIS cells. The cytotoxicity and MDR reversal activity of GlcN on cancer cells were measured by MTT assay. The effects of GlcN on MRP1 and MRP2 mRNA expression and function were evaluated by qRT-PCR and flow… CONTINUE READING
    1 Citations
    The Role of Exosomal microRNA in Cancer Drug Resistance
    • 4
    • PDF

    References

    SHOWING 1-10 OF 33 REFERENCES
    The novel IGF-IR/Akt–dependent anticancer activities of glucosamine
    • 14
    Molecular mechanisms of anticancer effects of Glucosamine.
    • 21