Glucosamine inhibits LPS-induced COX-2 and iNOS expression in mouse macrophage cells (RAW 264.7) by inhibition of p38-MAP kinase and transcription factor NF-kappaB.

@article{Rafi2007GlucosamineIL,
  title={Glucosamine inhibits LPS-induced COX-2 and iNOS expression in mouse macrophage cells (RAW 264.7) by inhibition of p38-MAP kinase and transcription factor NF-kappaB.},
  author={M. M. Rafi and P. Yadav and A. Rossi},
  journal={Molecular nutrition & food research},
  year={2007},
  volume={51 5},
  pages={
          587-93
        }
}
  • M. M. Rafi, P. Yadav, A. Rossi
  • Published 2007
  • Medicine, Biology
  • Molecular nutrition & food research
  • Glucosamine supplements are very promising nonsteroidal anti-inflammatory agents widely used for the treatment of arthritis in animals and humans. In this study, we have proposed the molecular mechanism underlying the anti-inflammatory properties of glucosamine hydrochloride (GLN) using mouse macrophage cell line (RAW 264.7). Treatment with GLN inhibited LPS-stimulated nitric oxide (NO) production. Western blotting and RT-PCR analysis showed that GLN treatment decreased LPS-induced inducible… CONTINUE READING

    Paper Mentions

    BLOG POST

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 37 CITATIONS, ESTIMATED 35% COVERAGE

    Toll-like receptor 4/nuclear factor-κB signaling pathway is involved in ACTG-toxin H-mediated anti-inflammatory effect

    VIEW 11 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2008
    2020

    CITATION STATISTICS

    • 2 Highly Influenced Citations