Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet.

@article{Hwang2015GlucosamineEB,
  title={Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet.},
  author={Ji-Sun Hwang and Ji-Won Park and Moonsuk Nam and Hyeongjin Cho and Inn-Oc Han},
  journal={Metabolism: clinical and experimental},
  year={2015},
  volume={64 3},
  pages={
          368-79
        }
}
OBJECTIVE This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. METHODS Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD) and the half of mice from CD and HFD provided with a solution of 10% (w/v) GlcN. Total cholesterol and nonesterified free fatty acid levels were determined. Glucose tolerance test and insulin tolerance test were performed. HepG2 human… Expand
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