Glucosamine HCl alters production of inflammatory mediators by rat intervertebral disc cells in vitro.

@article{Walsh2007GlucosamineHA,
  title={Glucosamine HCl alters production of inflammatory mediators by rat intervertebral disc cells in vitro.},
  author={Andrew J. L. Walsh and Conor W O'neill and J. Lotz},
  journal={The spine journal : official journal of the North American Spine Society},
  year={2007},
  volume={7 5},
  pages={
          601-8
        }
}
  • Andrew J. L. Walsh, Conor W O'neill, J. Lotz
  • Published 2007
  • Medicine
  • The spine journal : official journal of the North American Spine Society
  • BACKGROUND CONTEXT Studies on cartilage have shown anti-inflammatory effects of glucosamine related to inhibition of inflammatory mediators. Intradiscal injection of glucosamine has been proposed as a treatment for chronic discogenic low back pain. However, there have been no studies of the direct effects of glucosamine on disc cells. PURPOSE To determine the effects of glucosamine HCl on pro-inflammatory mediator production by intervertebral disc cells. STUDY DESIGN An in vitro… CONTINUE READING

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