Glucosamine, a naturally occurring amino monosaccharide, suppresses the ADP-mediated platelet activation in humans

@article{Hua2004GlucosamineAN,
  title={Glucosamine, a naturally occurring amino monosaccharide, suppresses the ADP-mediated platelet activation in humans},
  author={Jianyi Hua and Shiori Suguro and Kazuhisa Iwabuchi and Yuko Tsutsumi‐Ishii and Koji Sakamoto and Isao Nagaoka},
  journal={Inflammation Research},
  year={2004},
  volume={53},
  pages={680-688}
}
Abstract.Objective: To evaluate the anti-thrombotic action of glucosamine, a naturally occurring amino monosaccharide, platelets were stimulated with ADP in the presence of glucosamine, and its effects on platelet functions were examined.Materials and Methods: Human platelet-rich plasma was stimulated with 2.5 μM ADP in the presence of glucosamine (0.01 ~ 1 mM) or other aminosugars (N-acetyl-glucosamine, galactosamine or N-acetyl-galactosamine, 1 mM), and platelet aggregation was monitored… Expand
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