Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition.

@article{Sunehag1999GluconeogenesisIV,
  title={Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition.},
  author={Agneta L. Sunehag and Morey W Haymond and Richard J. Schanler and Peter J. Reeds and Dennis M. Bier},
  journal={Diabetes},
  year={1999},
  volume={48 4},
  pages={791-800}
}
Very low birth weight (VLBW) infants are dependent on total parenteral nutrition (TPN) to prevent hypoglycemia and provide a sufficient energy intake. However, diminished tolerance for parenteral glucose delivered at high rates frequently provokes hyperglycemia. We hypothesized that when their glucose supply is reduced to prevent hyperglycemia, VLBW infants can maintain normoglycemia via gluconeogenesis from glycerol and amino acids. Twenty infants born at 27 +/- 0.2 (mean +/- SE) gestational… CONTINUE READING