Glucocorticosteroids for primary biliary cirrhosis.

  title={Glucocorticosteroids for primary biliary cirrhosis.},
  author={Martin I Prince and Erik H\ojstrup Christensen and Christian N Gluud},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Primary biliary cirrhosis is a chronic progressive cholestatic liver disease of presumed autoimmune etiology, characterised by the destruction of small intrahepatic bile ducts and the eventual development of cirrhosis and liver failure. Its progression may be influenced by immunosuppression. Glucocorticosteroids are potent immunosuppressive agents, but they are associated with significant adverse effects, including osteoporosis. OBJECTIVES To systematically evaluate the beneficial… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 10 extracted citations

Primary biliary cirrhosis and liver transplantation.

Intractable & rare diseases research • 2012
View 1 Excerpt

Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat.

American journal of physiology. Gastrointestinal and liver physiology • 2012
View 2 Excerpts

Treatment of Primary Biliary Cirrhosis: A new challenge?

Hepatology research : the official journal of the Japan Society of Hepatology • 2010

Cholestasis and metabolic bone disease – a clinical review

Wiener Medizinische Wochenschrift • 2008
View 1 Excerpt

Similar Papers

Loading similar papers…