Glucocorticoids stimulate adrenergic differentiation in cultures of migrating and premigratory neural crest.

  title={Glucocorticoids stimulate adrenergic differentiation in cultures of migrating and premigratory neural crest.},
  author={Joel V Smith and Mireille Fauquet},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={4 8},
Glucocorticoid hormones stimulate catecholamine (CA) anabolism in a variety of adrenergic derivatives of the neural crest. We describe work performed to investigate the action of these steroids on the catecholaminergic differentiation of neural crest cells themselves. Crest was taken from the trunk level of 2-day quail embryos, before migration had begun, and was cultured in vitro. Adrenergic differentiation, characterized by the ability of the cultures to synthesize and store CA, was minimal… CONTINUE READING
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