Glucocorticoids may alter antioxidant enzyme capacity in the brain: kainic acid studies.

@article{McIntosh1998GlucocorticoidsMA,
  title={Glucocorticoids may alter antioxidant enzyme capacity in the brain: kainic acid studies.},
  author={Lacey J. McIntosh and Karen M Cortopassi and Robert Morris Sapolsky},
  journal={Brain research},
  year={1998},
  volume={791 1-2},
  pages={215-22}
}
Glucocorticoids (GCs) predispose hippocampal neurons to damage during metabolic stressors. One component of hippocampal GC-endangerment may be changes in neuronal defenses against oxidative challenge. Previous experiments showed a decrease in basal levels of copper/zinc superoxide dismutase (Cu/Zn SOD) and glutathione peroxidase (GSPx) in the brain of rats treated with GCs [L. McIntosh, K. Hong, R. Sapolsky, Glucocorticoids may alter antioxidant enzyme capacity in the brain: baseline studies… CONTINUE READING
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