Glucocorticoids in the management of peritumoral brain edema: a review of molecular mechanisms

Abstract

Peritumoral brain edema (PTBE) is mediated by blood-brain barrier breakdown. PTBE results from interstitial vasogenic brain edema due to vascular endothelial growth factor and other inflammatory products of brain tumors. Glucocorticoids (GCs) are the mainstay for treatment of PTBE despite significant systemic side effects. GCs are thought to affect multiple… (More)
DOI: 10.1007/s00381-016-3240-x

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@article{Murayi2016GlucocorticoidsIT, title={Glucocorticoids in the management of peritumoral brain edema: a review of molecular mechanisms}, author={Roger Murayi and Prashant Chittiboina}, journal={Child's Nervous System}, year={2016}, volume={32}, pages={2293-2302} }