Glucocorticoids do not reduce subjective fear in healthy subjects exposed to social stress.

  title={Glucocorticoids do not reduce subjective fear in healthy subjects exposed to social stress.},
  author={Leila Maria Soravia and Dominique J-F de Quervain and Markus Heinrichs},
  journal={Biological psychology},
  volume={81 3},
BACKGROUND Previous experiments in patients with phobia have shown that the administration of glucocorticoids reduces fear in phobic situations. Extensive evidence indicates that elevated glucocorticoid levels inhibit memory retrieval processes. In patients with phobia, exposure to a phobic stimulus (socio-evaluative stress test) provokes retrieval of stimulus-associated fear memory that leads to a fear response. It is therefore possible that glucocorticoids reduce phobic fear by inhibiting… CONTINUE READING

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Preventive effect of {beta}adrenoceptor blockade on glucocorticoid-induced memory retrieval deficits

  • de Quervain, D.J.-F, A. Aerni, B. Roozendaal
  • The American Journal of Psychiatry
  • 2007
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