Glucocorticoids as mediators of developmental programming effects.

@article{Khulan2012GlucocorticoidsAM,
  title={Glucocorticoids as mediators of developmental programming effects.},
  author={Batbayar Khulan and Amanda J Drake},
  journal={Best practice & research. Clinical endocrinology & metabolism},
  year={2012},
  volume={26 5},
  pages={689-700}
}
Epidemiological evidence suggests that exposure to an adverse environment in early life is associated with an increased risk of cardio-metabolic and behavioral disorders in adulthood, a phenomenon termed 'early life programming'. One major hypothesis for early life programming is fetal glucocorticoid overexposure. In animal studies, prenatal glucocorticoid excess as a consequence of maternal stress or through exogenous administration to the mother or fetus is associated with programming effects… CONTINUE READING

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