Glucocorticoids and phenobarbital induce murine CYP2B genes by independent mechanisms.

Abstract

BACKGROUND Genes for CYP of the 2B subfamily (CYP2B genes) have long been known to be inducible in murine liver by phenobarbital and phenobarbital-like inducers. More recently, it has become clear that glucocorticoids can also induce these genes by a mechanism independent of that of phenobarbital-like inducers. OBJECTIVE To summarize the evidence for the… (More)
DOI: 10.1517/17425250903234709

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