Glucocorticoids and invasive fungal infections.

  title={Glucocorticoids and invasive fungal infections.},
  author={Michail S. Lionakis and Dimitrios P Kontoyiannis},
  volume={362 9398},
Since the 1990s, opportunistic fungal infections have emerged as a substantial cause of morbidity and mortality in profoundly immunocompromised patients. Hypercortisolaemic patients, both those with endogenous Cushing's syndrome and, much more frequently, those receiving exogenous glucocorticoid therapy, are especially at risk of such infections. This vulnerability is attributed to the complex dysregulation of immunity caused by glucocorticoids. We critically review the spectrum and… CONTINUE READING
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