Glucocorticoids and fetal programming part 1: outcomes

  title={Glucocorticoids and fetal programming part 1: outcomes},
  author={Vasilis G. Moisiadis and Stephen G. Matthews},
  journal={Nature Reviews Endocrinology},
Fetal development is a critical period for shaping the lifelong health of an individual. However, the fetus is susceptible to internal and external stimuli that can lead to adverse long-term health consequences. Glucocorticoids are an important developmental switch, driving changes in gene regulation that are necessary for normal growth and maturation. The fetal hypothalamic–pituitary–adrenal (HPA) axis is particularly susceptible to long-term programming by glucocorticoids; these effects can… CONTINUE READING
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