Glucocorticoids and Rheumatoid Arthritis.

  title={Glucocorticoids and Rheumatoid Arthritis.},
  author={Joana Fonseca Ferreira and Alaa Abdelkhalik Ahmed Mohamed and P T J Emery},
  journal={Rheumatic diseases clinics of North America},
  volume={42 1},
  pages={33-46, vii}
Glucocorticoids (GCs) were discovered in the 1940s and were administered for the first time to patients with rheumatoid arthritis in 1948. However, side effects were subsequently reported. In the last 7 decades, the mechanisms of action for both therapeutic properties and side effects have been elucidated. Mechanisms for minimizing side effects were also developed. GCs are the most frequently used class of drugs in the treatment of rheumatoid arthritis because of their efficacy in relieving… CONTINUE READING