Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction.

@article{Mihailidou2009GlucocorticoidsAC,
  title={Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction.},
  author={Anastasia Susie Mihailidou and Thi Yen Loan Le and Mahidi Mardini and John W. Funder},
  journal={Hypertension},
  year={2009},
  volume={54 6},
  pages={
          1306-12
        }
}
Myocardial ischemia-reperfusion leads to significant changes in redox state, decreased postischemic functional recovery, and cardiomyocyte apoptosis, with development and progression of heart failure. Ischemia-reperfusion in the isolated perfused rat heart has been used as a model of heart failure. Clinically, mineralocorticoid receptor blockade in heart failure decreases morbidity and mortality versus standard care alone. The effects of corticosteroids on infarct area and apoptosis were… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 105 CITATIONS, ESTIMATED 37% COVERAGE

Aldosterone and Mineralocorticoid Receptors—Physiology and Pathophysiology

  • International journal of molecular sciences
  • 2017
VIEW 5 EXCERPTS
CITES BACKGROUND

Aldosterone Research: 65 Years, and Counting.

  • Vitamins and hormones
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

FILTER CITATIONS BY YEAR

2010
2019

CITATION STATISTICS

  • 4 Highly Influenced Citations

  • Averaged 7 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Clinical outcomes of dexamethasone-eluting stent implantation in ST-elevation acute myocardial infarction.

  • Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • 2007

Cardioprotective effects of eplerenone in the rat heart: interaction with locally synthesized or blood-derived aldosterone? Hypertension

W Chai, IM Garrelds, R de Vries, AHJ. Danser
  • 2006