Glucocorticoids, tumor necrosis factor-alpha, and epidermal growth factor regulation of pulmonary morphogenesis: a multivariate in vitro analysis of their related actions.

@article{Melnick1996GlucocorticoidsTN,
  title={Glucocorticoids, tumor necrosis factor-alpha, and epidermal growth factor regulation of pulmonary morphogenesis: a multivariate in vitro analysis of their related actions.},
  author={Michael M Melnick and Henry A. Choy and Tina Jaskoll},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1996},
  volume={205 4},
  pages={365-78}
}
The mouse lung commences development on embryonic day 11 as an epithelial evagination from the posterior pharyngeal wall into undifferentiated mesenchyme, this epithelium bifurcating to form the lung primordium. Branching morphogenesis, as well as terminal differentiation, requires epithelial-mesenchymal interactions utilizing precise regulatory controls. Not surprisingly, specific hormones and growth factors appear to play a key role in this regulation. We report here a series of experiments… CONTINUE READING
6 Citations
0 References
Similar Papers