Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner.

@article{Bourke2013GlucocorticoidSB,
  title={Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner.},
  author={Chase H. Bourke and Madiha Q Raees and Sanjana A. Malviya and Cory A Bradburn and Elisabeth B. Binder and Gretchen N. Neigh},
  journal={Psychoneuroendocrinology},
  year={2013},
  volume={38 1},
  pages={84-93}
}
Early life stress precipitates dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and this effect is most pronounced in females. The mechanisms that mediate female sensitivity to stress-induced HPA axis dysregulation are unknown. The purpose of this study was to determine whether sex moderates the effects of chronic adolescent stress on glucocorticoid receptor (GR) translocation and moderators of the GR system. Female adolescent rats with a history of chronic stress exposure… CONTINUE READING

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Stress-induced sex

C. H. 1291—1305. Bourke, C. S. Harrell, G. N. Neigh
2012
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