Glucocorticoid-regulated stability of a constitutively expressed mouse mammary tumor virus glycoprotein.

@article{Goodman1993GlucocorticoidregulatedSO,
  title={Glucocorticoid-regulated stability of a constitutively expressed mouse mammary tumor virus glycoprotein.},
  author={Lesley J. Goodman and Gary L. Firestone},
  journal={Molecular endocrinology},
  year={1993},
  volume={7 1},
  pages={94-103}
}
Glucocorticoids regulate the transport and processing of mouse mammary tumor virus (MMTV) glycoproteins in viral-infected HTC rat hepatoma cells. To begin to determine the role of cellular components involved in this steroid-mediated response, a constitutively expressed MMTV glycoprotein gene containing a mutation in the endoproteolytic cleavage site was used to simplify the viral maturation products. Expression of the uncleavable MMTV glycoprotein gene in transfected HTC rat hepatoma cells… CONTINUE READING