Glucocorticoid receptors in brain and pituitary of the lactating rat

@article{Meaney1989GlucocorticoidRI,
  title={Glucocorticoid receptors in brain and pituitary of the lactating rat},
  author={Michael J. Meaney and Victor Viau and David H. Aitken and Seema Bhatnagar},
  journal={Physiology & Behavior},
  year={1989},
  volume={45},
  pages={209-212}
}
The female rat exhibits elevated corticosterone levels throughout lactation, suggesting a possible dampening of the sensitivity of adrenocortical negative-feedback processes during this period. Negative-feedback within the adrenocortical axis is, in large part, mediated by an enhanced hormone receptor signal at a number of glucocorticoid target sites, including the pituitary, hypothalamus, and hippocampus. In the study reported here we have measured glucocorticoid receptor binding capacity in… CONTINUE READING

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