Glucocorticoid receptor signaling in health and disease.

  title={Glucocorticoid receptor signaling in health and disease.},
  author={Mahita Kadmiel and John Anthony Cidlowski},
  journal={Trends in pharmacological sciences},
  volume={34 9},
Glucocorticoids are steroid hormones regulated in a circadian and stress-associated manner to maintain various metabolic and homeostatic functions that are necessary for life. Synthetic glucocorticoids are widely prescribed drugs for many conditions including asthma, chronic obstructive pulmonary disease (COPD), and inflammatory disorders of the eye. Research in the past few years has begun to unravel the profound complexity of glucocorticoid signaling and has contributed remarkably to improved… CONTINUE READING
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