Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.

@article{Winsen2007GlucocorticoidRG,
  title={Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.},
  author={Lisa M L van Winsen and Tineke Hooper-van Veen and Elisabeth Fc van Rossum and Jan Willem Koper and Frederik Barkhof and Chris H. Polman and Bernard M. J. Uitdehaag},
  journal={Journal of neuroimmunology},
  year={2007},
  volume={186 1-2},
  pages={150-5}
}
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system, in which unknown environmental factors are thought to trigger disease in genetically susceptible persons. Glucocorticoids (GCs) play an important role in controlling chronic inflammatory diseases, like MS. Three polymorphisms in the glucocorticoid… CONTINUE READING