Glucocorticoid receptor gene and coronary artery disease: right idea, wrong gene variant?

  title={Glucocorticoid receptor gene and coronary artery disease: right idea, wrong gene variant?},
  author={Roland Rosmond},
  volume={42 2},
  pages={e3-4; author reply e3-4}
Artery Disease: Right Idea, Wrong Gene Variant? To the Editor: Recent data reported by Lin et al1 suggest that coronary artery disease (CAD) is associated with an Asn363Ser variant in exon 2 of the glucocorticoid receptor gene (GRL). The study is based on the notion that a dysfunctional glucocorticoid receptor may add to the adverse health effects of excessive cortisol concentrations. In a previous study, comprising Anglo-Celtic descent with a strong hereditability for hypertension and formerly… CONTINUE READING
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