Glucocorticoid receptor activity discriminates between progesterone and medroxyprogesterone acetate effects in breast cells

Abstract

The purpose of this article is to determine the tumorigenic potential of estradiol treatment (E2) when combined with either progesterone (P4) or medroxyprogesterone acetate (MPA) in normal luminal human breast cells (HBE) and in human breast cancer cells (T47-D, MCF-7). Proliferation profiles were evaluated, along with the gene transactivation activity… (More)
DOI: 10.1007/s10549-011-1394-5

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