Glucocorticoid receptor activation selectively hampers N-methyl-D-aspartate receptor dependent hippocampal synaptic plasticity in vitro.

Abstract

Corticosterone and exposure to stressful experiences have been reported to decrease hippocampal synaptic plasticity, in particular when relatively mild stimulation paradigms-presumably activating predominantly N-methyl-d-aspartate receptors-are being used. Using various stimulation paradigms and pharmacological approaches we tested therefore the hypothesis… (More)

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@article{Wiegert2005GlucocorticoidRA, title={Glucocorticoid receptor activation selectively hampers N-methyl-D-aspartate receptor dependent hippocampal synaptic plasticity in vitro.}, author={Olof Wiegert and Z D Pu and S. W. W. Shor and Manila Jo{\"e}ls and Harm J. Krugers}, journal={Neuroscience}, year={2005}, volume={135 2}, pages={403-11} }