Glucocorticoid production in the chicken bursa and thymus.

@article{Lechner2001GlucocorticoidPI,
  title={Glucocorticoid production in the chicken bursa and thymus.},
  author={Oskar Lechner and Harald Dietrich and Gerrit Jan Wiegers and Melanie S Vacchio and Georg Wick},
  journal={International immunology},
  year={2001},
  volume={13 6},
  pages={
          769-76
        }
}
Glucocorticoid (GC) hormones play an important role in thymic T cell selection and in the development of autoimmune diseases. Previous studies have shown that the mammalian thymus itself is able to produce GC. In order to assess the importance of these findings in terms of the evolutionary development of the immune system, we investigated the functional presence of steroidogenic enzymes in primary lymphoid organs of chickens, which represent one of the best studied non-mammalian species. To… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Paracrine glucocorticoid activity produced by alteration in chickens with spontaneous autoimmune thyroiditis

  • A. Pazirandeh, Y. Xue, I. Rafter, J. Sjovall, M. Jondal, S. Okret
  • J . Immunol .
  • 1999

Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of thehydroxysteroid dehydrogenase by rat sensory neurons and Schwann cells

  • K. Faessler, S. Schwarz, H. Dietrich, G. Wick
  • Eur . J . Neurosci .
  • 1999

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