Glucocorticoid-induced granulocytosis: contribution of marrow release and demargination of intravascular granulocytes.

  title={Glucocorticoid-induced granulocytosis: contribution of marrow release and demargination of intravascular granulocytes.},
  author={Mayumi Nakagawa and Takeshi Terashima and Yulia D'yachkova and Gregory P Bondy and James C. Hogg and Stephan F. van Eeden},
  volume={98 21},
BACKGROUND Glucocorticoid-induced granulocytosis has been attributed to enhanced release of polymorphonuclear leukocytes (PMNs) from bone marrow, delayed apoptosis, and reduced egress of PMNs into tissues. This study was designed to determine the relative contributions of PMNs released from the bone marrow and those entering the circulation from the marginated pool to the granulocytosis produced by a single dose of dexamethasone (2.0 mg/kg) in rabbits. METHODS AND RESULTS PMN transit through… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 59 extracted citations

Programmed Death 1 Blockade With Nivolumab in Patients With Recurrent Malignant Pleural Mesothelioma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer • 2018


Publications referenced by this paper.
Showing 1-10 of 24 references

L-selectin expression on polymorphonuclear leukocytes and monocytes in premature babies: reduced expression following dexamethasone treatment for bronchopulmonary dysplasia

D Weisman, SF Van Eeden, +4 authors GP. Bondy
J Pediatr • 1998

A non-radioisotopic method for tracing neutrophils in vivo using 59-bromo29-deoxyuridine.Am

S Bicknell, SF Van Eeden, +3 authors JC. Hogg
J Respir Cell Mol Biol • 1994

Similar Papers

Loading similar papers…