Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators.

@article{Minh2001GlucocorticoidHI,
  title={Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators.},
  author={Nguyet Le Minh and Francesca Damiola and François Tronche and G. Sch{\"u}tz and Ueli Schibler},
  journal={The EMBO journal},
  year={2001},
  volume={20 24},
  pages={7128-36}
}
The circadian timing system in mammals is composed of a master pacemaker in the suprachiasmatic nucleus (SCN) of the hypothalamus and slave clocks in most peripheral cell types. The phase of peripheral clocks can be completely uncoupled from the SCN pacemaker by restricted feeding. Thus, feeding time, while not affecting the phase of the SCN pacemaker, is a dominant Zeitgeber for peripheral circadian oscillators. Here we show that the phase resetting in peripheral clocks of nocturnal mice is… CONTINUE READING

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