Glucocorticoid-dependency of increased adiposity in a model of hypothalamic obesity.

Abstract

UNLABELLED It is known that rats treated, at neonatal age, with monosodium L-glutamate (MSG) develop neuroendocrine and metabolic abnormalities, resulting in a phenotype of hypothalamic obesity, characterized by increased adiposity, corticosteronemia and leptinemia. OBJECTIVE We explored whether adrenal manipulations could result in the reversion of this… (More)

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