Glucocorticoid antagonism by exercise and androgenic-anabolic steroids.

@article{Hickson1990GlucocorticoidAB,
  title={Glucocorticoid antagonism by exercise and androgenic-anabolic steroids.},
  author={Robert Charles Hickson and Susan M Czerwinski and Michael T. Falduto and A. P. Young},
  journal={Medicine and science in sports and exercise},
  year={1990},
  volume={22 3},
  pages={
          331-40
        }
}
This work evaluated the anticatabolic capacity of androgenic-anabolic steroids and exercise (contractile activity) in inhibiting skeletal muscle atrophy associated with excessive levels of circulating glucocorticoids. With androgenic-anabolic steroids, most binding studies indicate that they have very low binding specificity for the glucocorticoid receptor. Androgens may interact through their own receptor to interfere with glucocorticoid functioning at the gene level, but this remains unproven… CONTINUE READING
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