Glucocorticoid Resistance and the Immune Function in the Immunodeficiency Syndrome

@article{Norbiato1998GlucocorticoidRA,
  title={Glucocorticoid Resistance and the Immune Function in the Immunodeficiency Syndrome},
  author={G. Norbiato and M. Bevilacqua and T. Vago and M. Clerici},
  journal={Annals of the New York Academy of Sciences},
  year={1998},
  volume={840}
}
  • G. Norbiato, M. Bevilacqua, +1 author M. Clerici
  • Published 1998
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • Abstract: Glucocorticoids, the final product of HPA axis, and their receptors (GRs) on mononuclear cells are crucial mediators in the endocrine‐immune interaction. An alteration in GRs involving a lower receptor affinity (Kd) for glucocorticoids has been found in a group of advanced AIDS patients, who developed Addisonian symptoms (weakness, weight loss, hypotension, hyponatremia, and intense mucocutaneous melanosis) in spite of hypercortisolism and normal or slightly elevated values of ACTH… CONTINUE READING
    23 Citations
    Human immune deficiency virus (HIV) infection and the hypothalamic pituitary adrenal axis
    • 17
    Hypothalamic-pituitary-adrenal axis in HIV infection and disease.
    • 32
    Inescapable shock induces resistance to the effects of dexamethasone
    • 67
    • PDF
    Glucocorticoids: Protectors of the Brain during Innate Immune Responses
    • I. Glezer, S. Rivest
    • Biology, Medicine
    • The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
    • 2004
    • 82

    References

    SHOWING 1-10 OF 45 REFERENCES
    Cortisol resistance in acquired immunodeficiency syndrome.
    • 121
    Glucocorticoids and interferon-alpha in the acquired immunodeficiency syndrome.
    • 31
    • PDF
    Hypothalamic-pituitary-adrenal function in non-AIDS patients with advanced HIV infection.
    • 55
    Adrenal function in HIV infected patients.
    • 70
    Endogenous cortisol regulates immunoglobulin E-dependent late phase reactions.
    • 66
    • PDF
    alpha-Melanocyte stimulating hormone in the modulation of host reactions.
    • 210