Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis

  title={Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis},
  author={Christoph Anacker and Annamaria Cattaneo and Alessia Luoni and Ksenia Musaelyan and Patricia Ana Zunszain and Elena Milanesi and Joanna Rybka and Alessandra Berry and Francesca Cirulli and Sandrine Thuret and J. Price and Marco Andrea Riva and Massimo Gennarelli and Carmine M Pariante},
Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms underlying their effects are unknown. We, therefore, investigated the molecular signaling pathways mediating the effects of cortisol on proliferation, neuronal differentiation, and astrogliogenesis, in an immortalized human hippocampal progenitor cell line. In… CONTINUE READING