Glucocorticoid Regulation of Clock Gene Expression in the Mammalian Limbic Forebrain

  title={Glucocorticoid Regulation of Clock Gene Expression in the Mammalian Limbic Forebrain},
  author={Lauren A. Segall and Shimon Amir},
  journal={Journal of Molecular Neuroscience},
Glucocorticoids regulate a wide variety of functions, including synaptic plasticity, hypothalamic–pituitary–adrenal axis activation, conditional fear learning, metabolism, and sensitization to drugs of abuse. The diurnal secretion of glucocorticoids, driven by the mammalian master clock located in the suprachiasmatic nucleus of the hypothalamus, has been shown to induce and entrain clock gene expression in peripheral tissues. However, little attention has been given to the form and function of… CONTINUE READING


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The effects of corticosterone manipulation on the expression of the clock protein, PERIOD2

  • LA Segall, S Amir
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