Glucocorticoid Inhibition of Gags Biosynthesis: Possible Site of Action

Abstract

Glucocorticoid hormones inhibit the biosynthesis of glycosaminoglycans (GAGS) which are essential for normal skeletal growth. Previous studies have shown that these hormones alter both somatomedin, which stimulates GAGS biosynthesis, and the cartilage cell directly. We have further studied the effect of cortisol on GAGS biosynthesis in embryonic chick… (More)
DOI: 10.1203/00006450-197404000-00188

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Cite this paper

@article{Mcnatt1974GlucocorticoidIO, title={Glucocorticoid Inhibition of Gags Biosynthesis: Possible Site of Action}, author={M L Mcnatt and Barbara S Wingfield and E Richard Hughes and M. Joycelyn Elders}, journal={Pediatric Research}, year={1974}, volume={8}, pages={371-371} }