Gluco- and mineralocorticoids control adenylate cyclase in specific nephron segments.

@article{Doucet1990GlucoAM,
  title={Gluco- and mineralocorticoids control adenylate cyclase in specific nephron segments.},
  author={Alain R Doucet and C. Barlet-Bas and Sylvie Siaume-Perez and Chakir Khadouri and Sophie Marsy},
  journal={The American journal of physiology},
  year={1990},
  volume={258 4 Pt 2},
  pages={
          F812-20
        }
}
Adrenal insufficiency is associated with an impairment of kidney diluting and concentrating ability, defects that may result from alterations of vasopressin-induced adenosine 3',5'-cyclic monophosphate (cAMP) production. The purpose of this study were 1) to localize the sites of decreased vasopressin-stimulated adenylate cyclase (AC) activity along the nephron of adrenalectomized rats; 2) to determine whether the response of AC to other hormones is altered by adrenalectomy; 3) to evaluate… CONTINUE READING
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