Glucagonlike Peptide-1 (GLP-1) Participation in Ileal Brake Induced by Intraluminal Peptones in Rat

@article{Giralt1999GlucagonlikeP,
  title={Glucagonlike Peptide-1 (GLP-1) Participation in Ileal Brake Induced by Intraluminal Peptones in Rat},
  author={Magda Giralt and Patri Vergara},
  journal={Digestive Diseases and Sciences},
  year={1999},
  volume={44},
  pages={322-329}
}
The aim of this study was to determine themechanisms implicated in the gastrointestinal inhibitioninduced by ovoalbumin hydrolysate infusedintraluminally. We studied the site of action, thepossible implication of GLP-1, and the nervousmechanisms involved. We prepared anesthetizedSprague-Dawley rats with strain gauges in the antrum,duodenum, and proximal jejunum and a catheter in theduodenum or ileum for peptone infusion. Both intraduodenal(N = 6) and intraileal (N = 5) infusion of… CONTINUE READING