Glucagon regulation of energy metabolism.

  title={Glucagon regulation of energy metabolism.},
  author={Kristy M. Heppner and Kirk M Habegger and Jonathan Day and Paul T Pfluger and Diego P{\'e}rez-Tilve and Brian D. Ward and Vasily M Gelfanov and Steve C Woods and Richard D DiMarchi and Matthias Tsch{\"o}p},
  journal={Physiology & behavior},
  volume={100 5},
Glucagon has long been known as a counter-regulatory hormone to insulin of fundamental importance to glucose homeostasis. Its prominent ability to stimulate glycogenolysis and gluconeogenesis, has historically cast this peptide as one hormone where the metabolic consequences of increasing blood glucose levels, especially in obesity, are viewed largely as being deleterious. This perspective may be changing in light of emerging data and reconsideration of historic studies, which suggest that… CONTINUE READING
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