Glucagon-like peptide 2: a key link between nutrition and intestinal adaptation in neonates?

@article{Burrin2003GlucagonlikeP2,
  title={Glucagon-like peptide 2: a key link between nutrition and intestinal adaptation in neonates?},
  author={Douglas Burrin and Xinfu Guan and Barbara Stoll and Yvette Miata Petersen and Per Torp Sangild},
  journal={The Journal of nutrition},
  year={2003},
  volume={133 11},
  pages={3712-6}
}
This paper reviews the evidence from recent studies in young piglets to examine the hypothesis that glucagon-like peptide 2 (GLP-2) is a physiologically relevant hormonal signal linked to the intestinal adaptation associated with enteral nutrition in neonates. Observations that support the hypothesis include, 1) the GLP-2 secretory response to enteral nutrition is functional as early as late gestation, 2) parallel changes in intestinal growth and circulating GLP-2 occur in response to the… CONTINUE READING