Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig.

Abstract

Glucagon-like peptide 1 (GLP-1) metabolism was studied in halothane-anesthetized pigs (n = 7) using processing-independent (PI) and COOH-terminal (C) radioimmunoassays (RIA) and an enzyme-linked immunosorbent assay (ELISA) specific for biologically active GLP-1. Renal extraction of endogenous GLP-1 was detected by PI-RIA (33.1 +/- 13.3%) and C-RIA (16.0… (More)

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Cite this paper

@article{Deacon1996GlucagonlikeP1, title={Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig.}, author={Carolyn Fiona Deacon and Lone Pridal and Letty Klarskov and Martin Hammersh\oj Olesen and Jens Juul Holst}, journal={The American journal of physiology}, year={1996}, volume={271 3 Pt 1}, pages={E458-64} }