Glucagon-like peptide-1 is specifically involved in sweet taste transmission.

  title={Glucagon-like peptide-1 is specifically involved in sweet taste transmission.},
  author={Shingo Takai and Keiko Yasumatsu and Mayuko Inoue and Shusuke Iwata and Ryusuke Yoshida and Noriatsu Shigemura and Yuchio Yanagawa and Daniel J Drucker and Robert F Margolskee and Yuzo Ninomiya},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={29 6},
Five fundamental taste qualities (sweet, bitter, salty, sour, umami) are sensed by dedicated taste cells (TCs) that relay quality information to gustatory nerve fibers. In peripheral taste signaling pathways, ATP has been identified as a functional neurotransmitter, but it remains to be determined how specificity of different taste qualities is maintained across synapses. Recent studies demonstrated that some gut peptides are released from taste buds by prolonged application of particular taste… CONTINUE READING


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