Glucagon, in concert with insulin, supports the postabsorptive plasma glucose concentration in humans.

@article{Breckenridge2007GlucagonIC,
  title={Glucagon, in concert with insulin, supports the postabsorptive plasma glucose concentration in humans.},
  author={Suzanne M. Breckenridge and Benjamin A. Cooperberg and Ana Mar{\'i}a Arbel{\'a}ez and Bruce W. Patterson and Philip E. Cryer},
  journal={Diabetes},
  year={2007},
  volume={56 10},
  pages={2442-8}
}
OBJECTIVE Given the interest in glucagon antagonism as a potential treatment of diabetes, we tested the hypothesis that glucagon, in concert with insulin, supports the postabsorptive plasma glucose concentration in humans. RESEARCH DESIGN AND METHODS Following preliminary studies that indicated that a peripheral intravenous insulin dose of 0.1 mU x kg(-1) x min(-1) (lower than those used previously) provides basal insulin replacement and that a glucagon dose of 1.0 ng x kg(-1) x min(-1… CONTINUE READING
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