Glrb Allelic Variation Associated with Agoraphobic Cognitions, Increased Startle Response and Fear Network Activation

@article{Deckert2017GlrbAV,
  title={Glrb Allelic Variation Associated with Agoraphobic Cognitions, Increased Startle Response and Fear Network Activation},
  author={J. Deckert and H. Weber and P. Pauli and A. Reif},
  journal={European Neuropsychopharmacology},
  year={2017},
  volume={27}
}
Abstract The molecular genetics of panic disorder (PD) with and without agoraphobia (AG) are still largely unknown and progress is hampered by small sample sizes. We therefore performed a genome-wide association study with a dimensional, PD/AG - related anxiety phenotype based on the Agoraphobia Cognition Questionnaire (ACQ) in a sample of 1,370 healthy German volunteers of the CRC TRR58 MEGA study wave 1. A genome-wide significant association was found between ACQ and single non-coding… Expand