Glomerular inflammation in renal allografts biopsies after the first year: cell types and relationship with antibody-mediated rejection and graft outcome.

@article{Papadimitriou2010GlomerularII,
  title={Glomerular inflammation in renal allografts biopsies after the first year: cell types and relationship with antibody-mediated rejection and graft outcome.},
  author={John C. Papadimitriou and Cinthia B Drachenberg and Raghava B Munivenkatappa and Emilio Ramos and J. Nogueira and Charles J Sailey and David K Klassen and Abdolreza Haririan},
  journal={Transplantation},
  year={2010},
  volume={90 12},
  pages={1478-85}
}
BACKGROUND Antibody-mediated rejection manifests with glomerular and peritubular capillary inflammation and transplant glomerulopathy (TG). The role of glomerular inflammation (GI) components in the development of TG and their impact on outcome are incompletely understood. METHODS GI was quantified on hematoxylin-eosin, CD3, CD20, and CD68 stains on biopsies from 240 patients with grafts functioning more than or equal to 1 year. RESULTS A predominance of CD68+ cells followed by less… CONTINUE READING
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