Glomerular filtration rate estimation in patients with advanced chronic renal insufficiency based on serum cystatin C levels.

@article{Schck2003GlomerularFR,
  title={Glomerular filtration rate estimation in patients with advanced chronic renal insufficiency based on serum cystatin C levels.},
  author={Otto Sch{\"u}ck and Vladim{\'i}r Teplan and Anton{\'i}n Jabor and Milena {\vS}tollov{\'a} and Jelena Skibov{\'a}},
  journal={Nephron. Clinical practice},
  year={2003},
  volume={93 4},
  pages={c146-51}
}
BACKGROUND Cystatin C has an obvious advantage in the recognition of the initial stages of renal impairment. It is questionable whether cystatin C possesses the same benefit in follow-up of pre-dialysis patients. If cystatin C were also a sensitive marker of GFR in pre-dialysis patients, then it could be expected that, for the same degree of a decrease in GFR, the increase in S(cyst) would be higher than in S(cr) because of the significant increase in tubular secretion of creatinine in residual… CONTINUE READING
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