Glomerular deposition of immune complexes prepared with monomeric or polymeric IgA.


Clearance kinetics and renal deposition of soluble IgA immune complexes (IgA IC) were examined to determine the nephritogenic potential of IgA molecular form in mediating experimental IgA nephropathy. The immune complexes were prepared by mixing purified radiolabelled monomeric (mIgA) or polymeric (pIgA) IgA anti-dinitrophenyl (DNP), derived from MOPC-315… (More)


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