Glomerular deposition of immune complexes in dogs following natural infection with canine adenovirus

  title={Glomerular deposition of immune complexes in dogs following natural infection with canine adenovirus},
  author={William Ivan Morrison and Andrew S. Nash and N. G. Wright},
  journal={Veterinary Record},
  pages={522 - 524}
The renal lesions were studied in eight dogs which had either died as a result of acute canine adenovirus infection (Rubarth's disease) or were in various stages of recovery from the clinical disease. Using immunofluorescence techniques granular deposits of IgG were detected in the glomeruli of six dogs; four of these animals had similar glomerular deposits of canine adenovirus antigen. Eluates obtained from kidney tissue of four dogs were found to contain antiviral antibody. Histologically… Expand
Immunopathological aspects of canine renal disease.
The persistence of leptospiral antigen, alone or complexed with locally produced antibody, in the renal interstitium appears to be responsible for the marked cellular response in acute leptonospiral nephritis. Expand
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